South Africa has been a recipient country of the Global Fund since 2004 and has been disbursed over US$1.3 billion for HIV, TB and malaria.
With the support of the Global Fund , in South Africa;
- Between 2010 and 2020, the number of AIDS-related deaths decreased by 50%, from 164,000 annually to 83,000.
- The number of people living with HIV receiving antiretroviral (ARV) treatment tripled from 23% in 2010 to 72% in 2020.
- Coverage of medication that prevents mother-to-child transmission of HIV increased from 71% in 2010 to 95% in 2020.
- The success rate for treating multi-drug resistant TB increased from 40% in 2010 to 60% in 2017.
- The number of HIV patients with TB who have access to ARVs increased from 54% in 2010 to 85% in 2019.
The country is part of the Multicountry Africa (RMCC), Multicountry SEAF RMCC, Multicountry Southern Africa E8, Multicountry Southern Africa HIVOS, Multicountry Southern Africa MOSASWA, Multicountry Southern Africa SADC, Multicountry Southern Africa TIMS, and Multicountry Southern Africa WHC grants supported by the Global Fund.
As part of the operationalisation of Strategic Objective 3 of the Global Fund Strategy 2017 – 2022, the Breaking Down Barriers Initiative was initiated in 2020 in which South Africa participated. As part of this initiative, a Baseline Assessment was conducted in 2018 and a Mid-Term Assessment was commissioned by the Global Fund to present findings in South Africa in 2021. The mid-term assessment reported that there has been some progress since the baseline study in the scaling up of programs to address human rights-related barriers to TB and HIV services in the country, but for the most part it has been modest.
South Africa is one of the 5 African countries that co-hosted the Preparatory Meeting of the Global Fund Seventh Replenishment on 23-24 February 2022 and is both a donor to the Global Fund and an implementer of Global Fund-supported programs. South Africa has contributed ZAR 16 million and US$22.65 million to the Global Fund to date. The country pledged US$10 million for the Global Fund’s Sixth Replenishment, covering 2020-2022. The pledge doubles its previous commitment.