With nine years left to attain 2030 Sustainable Development Goals (SDGs), it is ever more urgent to ensure that communities of key, marginalised and vulnerable populations, and women and girls in all their diversity are at the centre of global health strategies and responses, even as the COVID-19 pandemic continues to ravage world economies and health systems. Amidst COVID-19: Putting the Last Mile First aims to highlight main barriers with recommendations that would lead us towards a coordinated, cohesive and collaborative approach towards achieving UHC and gender equality, and strengthening health and community systems without leaving anyone behind; and discuss the approaches towards sustainable financing at global, regional, and national levels to overcome COVID-19, achieve UHC and health-related SDG goals through people-centred, human rights-based and gender transformative approaches amidst COVID-19 pandemic challenges.