Critical moments that define our future.
A call for action and global solidarity.
The past few years have been immensely challenging for countless communities affected by colliding crises and the compounding effects of climate change, conflict and attacks on human rights, gender equality and civic spaces, even as the world recovers from the devastation of the COVID-19 pandemic.
Key and vulnerable populations – including men who have sex with men, transgender people, sex workers, people who use drugs, young people, migrants, prisoners, indigenous people, internally displaced populations, and the poor – now face deepened inequities and heightened risks of HIV, tuberculosis, malaria and other communicable diseases.
With 5 more years to 2030, now is the critical juncture in our fight to achieve the Sustainable Development Goals (SDG) targets of a world free from the burdens of HIV, tuberculosis & malaria, and promote sustainable, equitable healthcare towards universal health coverage (UHC).
We have to collectively step up to strengthen global health solidarity or we risk unravelling the progress we have made over the past two decades against three of the world’s most deadly epidemics.
As the world’s largest multilateral funder of global health grants in low- and middle-income countries, the Global Fund to Fight AIDS, Tuberculosis and Malaria (Global Fund) partnership has saved more than 65 million lives, cut the combined death rate from the three diseases by 63%, and contributed to stronger and more resilient health and community systems in over 100 countries.
This Eighth Replenishment, the Global Fund needs US$18 billion to protect the remarkable gains this global partnership has achieved and:
- Save an additional 23 million lives between 2027-2029;
- Avert 400 million new infections or cases between 2027-2029;
- Deliver a return on investment of 1:19 for every dollar invested, resulting in US$323 billion of health and economic gains over 2027-2029; and
- Catalyse improved and more targeted domestic investments for HIV, TB, malaria and health and community systems.
In these increasingly complex, fractured and unpredictable geopolitical contexts, global solidarity and renewed commitment are needed more now than ever. We must mobilise greater domestic resources for health and achieve a fully resourced Global Fund if we are to close the gaps, stabilise, sustain, and accelerate our progress towards the 2030 goals and UHC.
#HereIAm at this critical juncture in the fight against HIV, TB and malaria, ready as communities and civil society to stand alongside donors and implementers as #OneWorldOneFight…
During these moments that define us…
#MoreNowThanEver!
Key Messages
As communities and civil society, we stand united in calling on governments and duty-bearers to:
Let Communities Lead
As the frontliners in the fight against the three diseases, communities living with and/or affected by HIV, TB and malaria possess invaluable first-hand experience and knowledge. With community leadership at the forefront, we are able to leverage synergies and partnerships to ensure health programmes are contextualised, inclusive, and effective across all communities, including youth, women and girls.
Connect The Gaps
Meaningful engagement with all key populations and vulnerable groups is crucial for enabling equitable and quality access to health for all. Marginalised communities often face barriers to healthcare services due to accessibility and affordability. Therefore, we need health programmes that adopt a people-centred, gender-inclusive approach towards providing integrated and holistic health care.
Uphold Accountability For All
As a global partnership, we must each be accountable in meeting our resourcing and impact commitments in order to maintain the excellent returns on health investments. We need meaningful, transparent and open involvement of all stakeholders to develop innovative and differentiated approaches that ensure rigour and reach across all key and vulnerable populations.
Protect Our Rights, Our Lives
To be effective, health programmes for key populations and vulnerable groups should seek to protect lives and respect human dignity when operating in oppressive and discriminatory environments. Promoting health and wellbeing goes hand-in-hand with empowering more meaningful civic participation and enabling legal environments for marginalised communities. As we progress towards UHC, we should also empower individuals towards self-determination.
Campaign Symbol
Five-Pointed Stars
The five-pointed star is a universal symbol of hope and good fortune, with deep historical meanings. Stars are a symbol of guidance and light during challenging times, a representation of unity despite diversities, a mark of love, support and admiration, as well as an historical sign of health & protection.
Strip-Folded Paper Stars
Paper stars, folded using a single strip of coloured paper, is a traditional craft that is often given as a gift of love and good luck to others. Paper stars sometimes contain messages of care and hope written on the strip before folding.
News and Updates from the
Eighth Replenishment
World Mental Health Day 2025
Sign-On Letter to the President of Indonesia | Eighth Replenishment
Sign-On Letter to the Prime Minister of the United Kingdom | Eighth Replenishment
6,175 Japanese Citizens Sign Petition Calling for Strengthened Contributions from Japan to the Global Fund
Sign-On Letter to the Chancellor of Germany | Eighth Replenishment
Resources & Social Media
Please check out our Resources Page for materials and tools for use on social media, and follow us on our social media platforms!
#MoreNowThanEver partnerships across all sectors, including the private sector is necessary for impact for health as a right for all as we are gearing up for the last mile of #8thReplenishment of @GlobalFund!
@GFAN_Africa @GFadvocates @CS4MEglobal @GFANAP
This #WorldMentalHealthDay, GFAN AP, @UnitedGMH & @sevenallianceap call on ALL stakeholders to ensure mental health is fully funded & integrated in HIV, TB & malaria responses - through a successful @GlobalFund #8thReplenishment #MoreNowThanEver!
📜https://gfanasiapacific.org/2025/10/world-mental-health-day-2025/